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Cetyl Myristoleate

What is cetyl myristoleate?

Cetyl myristoleate is a form of a myristoleic acid, a type of fatty acid. It is a supplement used to treat the pain, the decreased range of motion, and the mobility consequences of osteoarthritis in dogs. The mechanism of action is unknown, but it may be like that of omega-3 fatty acids.

Dietary supplements are substances that can be used to supplement the diet, such as vitamins, minerals, amino acids, herbs, botanicals, enzymes, and probiotics. While many supplements are sold over the counter, they still contain ingredients that have biological effects that should be managed by your veterinarian. Follow your veterinarian’s directions and cautions very carefully as their directions may be significantly different from those on the label.

There are differences in how countries regulate supplements. In the United States, these substances are not as vigorously regulated by the FDA as other medications, which means they can be sold without the manufacturer proving their effectiveness, safety, and without a guarantee of consistent or accurately reported ingredients. In Canada, products that have been evaluated for quality, safety, and effectiveness by Health Canada and authorized for sale will have a license number on the label.


How effective is cetyl myristoleate?

Limited studies in animals have been performed, but there are a few scientific studies that have found it effective for mild osteoarthritis in humans.


How is cetyl myristoleate given?

Cetyl myristoleate is given by mouth in the form of a capsule or is used topically in the form of a cream. The oral form can be given with or without food; however, if stomach upset occurs when given on an empty stomach, give future doses with food.


What if I miss giving my pet the supplement?

If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give it at the next scheduled time, and return to the regular dosing schedule. Never give your pet two doses at once or give extra doses.


Are there any potential side effects?

Studies are limited for this supplement and therefore information regarding side effects is also limited. However, there does not appear to be any side effects except for rare mild gastrointestinal upset such as decreased appetite, vomiting, or diarrhea.


Are there any risk factors for this supplement?

Studies are limited for this supplement and therefore information regarding risk factors is also limited. Due to the limited information, cetyl myristoleate should be used cautiously in very young, debilitated, pregnant, or nursing pets.


Are there any drug interactions I should be aware of?

There are no known drug interactions with cetyl myristoleate.

Vitamins, herbal therapies, and supplements have the potential to interact with each other, as well as with prescription and over the counter medications. It is important to tell your veterinarian about any medications (including all vitamins, supplements, or herbal therapies) that your pet is taking.


Is there any monitoring that needs to be done with this supplement?

There is no specific monitoring that needs to be done while your pet is taking this medication. Your veterinarian may monitor your pet to be sure that the medication is working.


How do I store cetyl myristoleate?

In general, store in a cool, dry place at room temperature and protect from light. However, there are many manufacturers of this supplement, so always follow the storage instructions on the label.


What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.

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